Wednesday, November 30, 2022
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FDA Officials Warn Of Brain Swelling, Vision Loss In Minors Using Puberty Blockers

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FDA Officials Warn Of Brain Swelling, Vision Loss In Minors Using Puberty Blockers

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Puberty Blockers

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“O come, let us worship and bow down: let us kneel before the LORD our maker.”  Psalms 95:6 (KJV) 

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Listen to the article below

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[fusion_dropcap boxed=”no” boxed_radius=”” class=”” id=”” color=”” text_color=””]P[/fusion_dropcap]uberty blockers, known as gonadotropin-releasing hormone (GnRH) substances, received a warning from U.S. Food and Drug Administration (FDA) officials earlier this month, saying the drug could cause brain swelling, loss of vision, and serious risks for children injecting the hormone.

Officials said a plausible association between using puberty blockers and pseudotumor cerebri, which displays symptoms similar to a brain tumor, was identified in six young girls between the ages of 5 and 12.

“Five were undergoing treatment for central precocious puberty and one for transgender care,” FDA officials report. “The onset of pseudotumor cerebri symptoms ranged from three to 240 days after GnRH agonist initiation.”

Such symptoms in the patients included visual disturbances, headaches, and vomiting. Other effects GnRH agonists caused were an increase in blood pressure, brain swelling, and abducens neuropathy.

A spokesperson from the FDA told Formulary Watch the cases were considered clinically serious and determined that a warning should be added to all GnRH agonist products approved for pediatric patients.

“Although the mechanism by which GnRH agonists may lead to development of pseudotumor cerebri has not been elucidated, and patients with CPP may have a higher baseline risk of developing pseudotumor cerebri compared with children without CPP,” the spokesperson said. “This potential serious risk associated with GnRH agonists justifies inclusion in product labeling.”

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